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Free vs. Total Testosterone

Why the active portion matters.

Quick answer

Total testosterone is all the testosterone in your blood. Most of it is bound to proteins: roughly 44 to 65% is tightly bound to sex hormone-binding globulin (SHBG) and about 33 to 54% is loosely bound to albumin, while only about 2% circulates as free testosterone. Free and albumin-bound testosterone together are called bioavailable testosterone, the portion the body can readily use. A man can have normal total testosterone but low free testosterone if his SHBG is high, which often happens with age. The American Urological Association uses a total testosterone below 300 ng/dL, together with symptoms, as a guide for low testosterone. Testing is done with a morning blood test, repeated on a second day. Sleep, exercise, healthy weight and limiting alcohol support healthy testosterone levels.

Key takeaways

When men talk about testosterone, they usually mean a single number. But the testosterone in your blood exists in different forms, and the difference can matter.

The three forms of testosterone

FormApprox. shareAvailable to the body?
Bound to SHBG44–65%No, tightly bound
Bound to albumin33–54%Yes, loosely bound
Free testosterone~2%Yes, fully active

Free plus albumin-bound testosterone is called bioavailable testosterone.

Why free testosterone matters

SHBG tends to rise with age and with some health conditions, so a man's total testosterone can look normal while his free testosterone is low. Research has linked low free testosterone to symptoms such as low libido and erection changes, even in men with normal total levels.

Common signs of low testosterone

How testing works

  1. Morning blood test (levels peak in the morning)
  2. Repeat on a second day to confirm
  3. Your doctor may also check SHBG, free testosterone, LH and other hormones

The American Urological Association uses a total testosterone below 300 ng/dL, together with symptoms, as a guide for diagnosing low testosterone. Reference ranges vary by laboratory.

Habits that support healthy testosterone

Some nutrients, such as boron and tongkat ali, have been studied for their role in healthy testosterone levels and are discussed in ErecSurge's research references.

See a doctor if you have symptoms of low testosterone. Testosterone therapy is a prescription treatment with its own risks and needs medical supervision.

Sources

  1. Mulhall JP, et al. "Evaluation and management of testosterone deficiency: AUA guideline." Journal of Urology, 2018.
  2. Travison TG, et al. "Harmonized reference ranges for circulating testosterone levels in men." Journal of Clinical Endocrinology & Metabolism, 2017.
  3. Antonio L, et al. "Low free testosterone is associated with hypogonadal signs and symptoms in men with normal total testosterone." Journal of Clinical Endocrinology & Metabolism, 2016.

Common questions

What is free testosterone?

The roughly 2% of testosterone not bound to proteins, fully available to the body.

Can free testosterone be low if total is normal?

Yes, especially when SHBG is high, which often happens with age.

How is testosterone tested?

With a morning blood test, repeated on a second day.

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